Design of oligothiophene-based tetrazoles for laser-triggered photoclick chemistry in living cells.

نویسندگان

  • Peng An
  • Zhipeng Yu
  • Qing Lin
چکیده

A 405 nm light-activatable terthiophene-based tetrazole was designed that reacts with a fumarate dipolarophile with the second-order rate constant k2 exceeding 10(3) M(-1) s(-1). The utility of this laser-activatable tetrazole in imaging microtubules in a spatiotemporally controlled manner in live cells was demonstrated.

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عنوان ژورنال:
  • Chemical communications

دوره 49 85  شماره 

صفحات  -

تاریخ انتشار 2013